IIT JAM Biotechnology 2022 Question Paper with Answer Key

Which of the following is involved in innate immune response in higher mammals?

1. AT cell antigen receptor
2. BB cell antigen receptor
3. CToll-like receptor
4. DMajor histocompatibility complex-II molecule

Which among the following belongs to the family “Retroviridae”?

1. AHuman Immunodeficiency virus
2. BEbola virus
3. CDengue virus
4. DInfluenza virus

Which of the following is a glycolipid?

1. ACerebroside
2. BPhosphatidylcholine
3. CPhosphatidylserine
4. DCardiolipin

Which of the following bacterial component contains “dipicolinic acid”?

1. AEndospore
2. BCapsule
3. CFlagella
4. DPili

The fossilization process in which mineral rich water penetrates through the pores of decomposed organic matter is known as _____.

1. ACarbonization
2. BChemical fossilization
3. CPetrifaction
4. DMicrofossilization

A random fluctuation in gene frequency is called

1. AGenetic drift
2. BGenetic load
3. CPanmixis
4. DGenetic shift

The number of “Barr Bodies” present in a somatic cell of a woman suffering from Turner syndrome is ____.

1. A0
2. B1
3. C2
4. D3

Which of the following are produced by Mangrove trees to survive in the waterlogged swampy forests?

1. ATrichomes
2. BPneumatophores
3. CSpermatophores
4. DCambia

Indeterminate growth in plants is due to the presence of perpetually undifferentiated tissues, called as ______.

1. ATracheids
2. BMeristems
3. CParenchyma
4. DSclerenchyma

The osmotic potential (ψ) of pure water is _____ MPa.

1. A−1
2. B0
3. C0.1
4. D10

Bacteria containing a tuft of flagella that comes out from one pole is called ___.

1. ALophotrichous
2. BPeritrichous
3. CMonotrichous
4. DAmphitrichous

Which of the following activity is associated with Klenow fragment?

1. A5′-3′ exonuclease activity
2. B5′-3′ endonuclease activity
3. CPolymerase activity
4. D3′-5′ endonuclease activity

A frameshift mutation is caused by ____.

1. A5-Bromouracil
2. BAcridine
3. CGlutathione
4. DHypoxanthine

The zone of a pond system where respiration is more than production is called as _____.

1. ALimnetic zone
2. BLittoral zone
3. CEpilimnion zone
4. DBenthic zone

An organism that causes obstruction of lymphatic system in humans is ____.

1. ABorrelia burgdorferi
2. BBrucella abortus
3. CYersinia pestis
4. DWuchereria bancrofti

A man having a dominant genetic trait (TT genotype) can taste phenylthiocarbamide (PTC), marries a woman who cannot taste PTC. The PTC tasting ability of their biological son and daughter is

1. ASon taster; Daughter non-taster
2. BDaughter taster; Son non-taster
3. CBoth are non-tasters
4. DBoth are tasters

Which of the following enzymes is absent in a person suffering from Alkaptonuria?

1. ATyrosinase
2. BHomogentisic acid oxidase
3. CCatechol dioxygenase
4. DPhenylalanine hydroxylase

The bacterium that can tolerate high concentrations of salt and also ferment mannitol is

1. AStaphylococcus aureus
2. BStaphylococcus epidermis
3. CStreptococcus pyogenes
4. DSerratia marcescens

Match the following

1. AP-1, Q-3, R-4, S-2
2. BP-4, Q-3, R-1, S-2
3. CP-2, Q-3, R-1, S-4
4. DP-3, Q-4, R-1, S-2

The major product formed in the given reaction is

1. A
2. B
3. C
4. D

DNA gyrase can

1. Acut single-stranded DNA
2. Brelax supercoiled DNA
3. Cintroduce negative supercoiling in DNA
4. Dnot utilize ATP

The stationary phase of cation-exchange chromatography can be

1. ADEAE-cellulose
2. BCM-cellulose
3. CSephadex G-50
4. DHeparin-Sepharose

Components of a Transmission Electron Microscope are

1. AElectron gun, objective lens, positron beam, projector lens
2. BNeutron beam, projector lens, objective lens, evacuated tube
3. CElectron beam, projector lens, objective lens, condenser lens
4. DX-ray beam, projector lens, objective lens, condenser lens

In a honey bee population, the workers are infertile but protect the queen from intruders and help in reproduction. This is an example of

1. AK selection
2. BSexual selection
3. CKin selection
4. DDisruptive selection

For an enzyme following Michaelis-Menten kinetics, when [S] = K_M then, the velocity v is

([S] is substrate concentration, K_M is Michaelis constant, V_max is maximal velocity)

1. A[S] × V_max
2. B0.75 × V_max
3. C0.5 × V_max
4. DK_M × V_max

The net equation for aerobic glycolysis is

1. AGlucose + 2ATP → 2 lactate + 2ADP + 2P_i
2. BGlucose + 2ADP + 2P_i + 2NAD⁺ → 2 pyruvate + 2ATP + 2NADH + 2H₂O + 4H⁺
3. CGlucose + 2ADP + 2P_i → 2 pyruvate + 2ATP + 2H₂O
4. DGlucose + 2ADP + 2P_i + 2NAD⁺ → 2 lactate + 2ATP + 2NADH + 2H₂O + 4H⁺

In the electron transport chain, flavin mononucleotide (FMN) can adopt ______ as the highest oxidation state and is capable of accepting or donating _____ electrons, respectively.

1. A2; 2 or 3
2. B2; 1 or 2
3. C3; 2 or 3
4. D3; 1 or 2

In bacteria, the σ factor that plays a major role in transcription during the stationary phase is

1. Aσ⁷⁰
2. Bσ⁵⁴
3. Cσ²⁸
4. Dσ³²

A rise in cytosolic calcium ion concentration just after fertilization in a sea urchin egg leads to

1. AFormation of fertilization envelope
2. BAcrosomal reaction
3. CFormation of vegetal pole
4. DFormation of animal pole

In a nephron, _____ follows the ascending limb of the “loop of Henle”.

1. ADescending limb
2. BDistal tubule
3. CCollecting tubule
4. DProximal tubule

Transpirational pull that extends down to the roots in plants can be interrupted by

1. AProcess of cavitation
2. BProcess of gravitation
3. CFormation of water vapor pockets
4. DPositive pressure in xylem sap

Transfer of plasmids into animal cells can be achieved by

1. AElectroporation
2. BLiposome-mediated process
3. CCalcium chloride treatment
4. DSucrose treatment

Archaeal cell membranes contain lipids that are

1. AEther linked
2. BEster linked
3. CBranched alkyl chain
4. DLinear alkyl chain

Which of the following are producers in an ecological system?

1. AMacrophytes
2. BPhytoplanktons
3. CZooplanktons
4. DCyanobacteria

Which of the following acts as wound hormones in plants?

1. AEthylene
2. BCytokinins
3. CAbscisic acid
4. DDextrin

The enriched media used to facilitate the growth of fastidious microorganisms are

1. ASelenite F broth
2. BBlood agar
3. CChocolate agar
4. DLoeffler’s serum

Match the bacterial structure to function

1. A(i)-(b), (ii)-(d)
2. B(i)-(d), (ii)-(a)
3. C(i)-(c), (ii)-(b)
4. D(i)-(d), (ii)-(c)

Identify the correct pairs:

1. A(i)-(d)
2. B(ii)-(b)
3. C(iii)-(a)
4. D(iv)-(c)

A single copy of an allele in sickle-cell heterozygous individuals reduces the frequency and severity of malaria. The reason for this is

1. ALow oxygen binding capacity of hemoglobin
2. BSingle amino acid substitution in hemoglobin deforms the red blood cells
3. CAbnormal hemoglobin is toxic for malaria parasite
4. DMalaria parasite escapes the deformed red blood cells

The correct statement/s for bimolecular nucleophilic substitution reactions is/are

1. AIt goes through a carbocation formation
2. BThere is an inversion of configuration if the reacting center is chiral
3. CReaction is enhanced when carried out in polar solvents
4. DThe reaction intermediate is trigonal bipyramidal

A deck of ten cards is given to you as shown below in the figure. One card is drawn at random from this deck. The probability of selecting a number less than 9 is ____. (to one decimal place)

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The average of all positive even integers less than or equal to 40 is ___.

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The smallest positive (non-zero) integer “n” for which the expression ((1 + i)/(1 − i))ⁿ = 1 holds true, is ___.

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Given that

A = (sinθ cosθ tanθ + sinθ cosθ cotθ), the value of A is

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An object is placed at the principal focus of a concave lens of focal length 10 cm. The image will be formed at _____ cm, between the optical center and the focus of the lens on the same side of the object.

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What is the maximum number of hydrogen bonds that a water molecule can make in the liquid state?

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How many pairs of autosomal chromosomes are there in normal humans?

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Calculate the temperature (in K) at which the resistance of a metal becomes 20% more than its resistance at 300 K. The value of the temperature coefficient of resistance for this metal is 2.0 × 10⁻⁴ /K.

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In the ¹H NMR spectrum of ethanol at 400 MHz, the methyl group splits into _________ number of peaks.

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In a denaturing polyacrylamide gel electrophoresis experiment, pure intact adult human hemoglobin will yield ________ (number) bands.

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A man throws a ball vertically up in the air with an initial velocity v₁ such that it reaches a height of 12 m with a speed of 12 m/s. If he throws the same ball vertically up with an initial velocity v₂ such that it reaches a maximum height of 12 m. Calculate v₁/v₂. (up to 2 decimal places)

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What is the acceleration due to gravity (m/s²) on the surface of a planet if its radius is 1/4^th that of earth and its mass is 1/80^th that of earth? Assume that the gravity on the surface of the earth is 10 m/s².

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In a randomly mating population, the frequency of ‘A’ allele is 0.7. What is the frequency of ‘Aa’ genotype in the next generation according to Hardy-Weinberg’s law? (up to two decimal places)

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The potential difference to accelerate an electron was quadrupled. By what factor does the de Broglie wavelength of the electron beam change?

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A 500 nm light is used for imaging in a confocal microscope. What will be the best resolution (in nm) of this microscope?

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Assuming the molecule shown below is aromatic, the value of “n” according to “Hückel’s rule” is

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In an actively growing population from a single bacterium, 1,048,576 cells are present after 20^th generation. How many cells were there in 5^th generation?

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A double stranded DNA molecule of total 5000 base pairs long, has a melting temperature of 85 °C. What will be the % AT base pairs in this sample? (up to one decimal place).

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How many GTP molecules are required for the translocation of tRNA from P site to E site during translation elongation process in bacteria?

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Amongst the molecules given below, the total number of molecules that have at least one sp² hybridized atom is __________.

C₆H₆, NO₂, BF₃, H₂O₂, SO₂, C₂H₂, L-Tryptophan

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